This year, it's the villains who get the focus. For all their grandiose plans of world domination, they're only compensating for the one thing they have been deprived of: acceptance. That is, if 'Despicable Me' and the just opened 'Megamind' would have us believe.
Gru's three orphans grow on him, and his long-suppressed paternal instincts rise to the fore as he meets his new-found responsibilities like a man. Megamind gets afflicted with reverse Stockholm syndrome -- he kidnaps the same female reporter so often he eventually falls for her. When this pair of miscreants realize their human sides, they gain a purpose bigger than themselves and eventually make good.
If only real evil were so easy to identify. But it's the consequences of momentary idiocy; or blind, unquestioning faith; or misguided righteousness that are truly horrific. In fact, often the greatest evils are perpetrated by those who believe they are acting for the greatest good. Think about that for a bit.
Oh, and while we're on the topic of cartoon characters, alas, poor Sid. I knew him, Manfred. Sniff.